Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Oct 29;5:15768. doi: 10.1038/srep15768

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

PMC Copyright notice

(A) Immunofluorescence of IRF1 in intact unstimulated and LPS-stimulated RAW264.7 cells was examined. IRF1 accumulated in the nucleus at 4 hours of LPS stimulation and then returned to the basal state at 24 hours. On the other hand, IRF1 stayed in the nucleus at 24 hours of stimulation with LPS and 5AZ. The nuclei were readily identified with DAPI. (B) Effect of 5AZ on the protein expressions of iNOS, IRF1, and STAT1. Cells were treated with LPS in the absence or presence of 5AZ for 4 hours or 24 hours. Results expressed as mean ± SD. *Significantly different from cells treated with LPS alone, p < 0.05.