We assessed differences in major tau kinases in female rat hippocampus under basal conditions (not stressed) in virgin (V), lactating (L), or weaned (W) (N=5, each), Western blot analysis was performed using antibodies specific to GSK3, ERK, and JNK. We found that NS lactating rats have significantly less hippocampal GSK3-α compared to both non-stressed virgin and weaned rats (p = 0.016, p = 0.016). There were no significant differences in ERK or JNK. Data are presented as percent change from the V condition ± SEM.