Table 1.
Adjusted means of anthropometric and biochemical variables between groups with NAFLD and without NAFLD, stratified by overweight/obesity and metabolic status
| BMI <23 kg/m2 | BMI ≥23 kg/m2 | |||||||
|---|---|---|---|---|---|---|---|---|
| Metabolically healthy | Metabolically at-risk | Metabolically health | Metabolically at-risk | |||||
| Without NAFLD | With NAFLD | Without NAFLD | With NAFLD | Without NAFLD | With NAFLD | Without NAFLD | With NAFLD | |
| N | 3625 | 332 | 437 | 203 | 1776 | 1847 | 605 | 1936 |
| Age (years)* | 44.81 ± 0.25 | 48.77 ± 0.70 | 56.17 ± 0.69 | 56.41 ± 0.92 | 50.06 ± 0.34 | 50.40 ± 0.32 | 56.14 ± 0.59 | 53.61 ± 0.30 |
| BMI (kg/m2) | 20.59 ± 0.03 | 21.78 ± 0.06 | 21.26 ± 0.06 | 21.93 ± 0.07 | 24.75 ± 0.04 | 26.08 ± 0.05 | 25.10 ± 0.07 | 26.73 ± 0.06 |
| SBP (mmHg) | 116.12 ± 0.23 | 116.34 ± 0.75 | 128.48 ± 0.66 | 128.30 ± 0.96 | 120.67 ± 0.33 | 122.16 ± 0.33 | 130.23 ± 0.56 | 131.37 ± 0.32 |
| DBP (mmHg) | 72.90 ± 0.16 | 74.43 ± 0.53 | 81.30 ± 0.47 | 81.28 ± 0.68 | 76.30 ± 0.23 | 78.00 ± 0.23 | 82.56 ± 0.40 | 84.43 ± 0.23 |
| ALT (U/L) | 19.08 ± 0.23 | 26.58 ± 1.54 | 21.54 ± 0.88 | 25.14 ± 0.98 | 25.25 ± 0.83 | 30.32 ± 0.50 | 23.93 ± 0.60 | 35.19 ± 0.58 |
| Total cholesterol (mmol/L) | 4.40 ± 0.01 | 4.72 ± 0.05 | 4.58 ± 0.04 | 4.81 ± 0.06 | 4.58 ± 0.02 | 4.81 ± 0.02 | 4.74 ± 0.04 | 5.00 ± 0.02 |
| Triglycerides (mmol/L) | 0.86 ± 0.02 | 1.29 ± 0.07 | 1.78 ± 0.06 | 2.70 ± 0.09 | 1.04 ± 0.03 | 1.32 ± 0.03 | 1.96 ± 0.05 | 2.73 ± 0.03 |
| LDL cholesterol (mmol/L) | 2.64 ± 0.01 | 2.93 ± 0.04 | 2.73 ± 0.04 | 2.77 ± 0.05 | 2.85 ± 0.02 | 3.07 ± 0.02 | 2.84 ± 0.03 | 2.92 ± 0.02 |
| HDL cholesterol (mmol/L) | 1.54 ± 0.00 | 1.45 ± 0.02 | 1.31 ± 0.01 | 1.21 ± 0.02 | 1.43 ± 0.01 | 1.38 ± 0.01 | 1.23 ± 0.01 | 1.20 ± 0.01 |
| Triglycerides/HDL-C | 0.58 ± 0.04 | 0.95 ± 0.12 | 1.55 ± 0.10 | 2.47 ± 0.15 | 0.76 ± 0.05 | 1.00 ± 0.05 | 1.86 ± 0.09 | 2.66 ± 0.05 |
| FPG (mmol/L) | 4.94 ± 0.02 | 5.58 ± 0.07 | 6.04 ± 0.06 | 6.45 ± 0.08 | 5.00 ± 0.03 | 5.53 ± 0.03 | 5.67 ± 0.05 | 5.98 ± 0.03 |
| Uric acid (mmol/L) | 273.14 ± 1.11 | 294.62 ± 3.61 | 289.96 ± 3.15 | 309.97 ± 4.61 | 291.76 ± 1.57 | 314.72 ± 1.56 | 303.25 ± 2.69 | 332.81 ± 1.53 |
Metabolically healthy and metabolically at-risk were defined in the definition section
Data are presented as mean (SE)
Data adjusted for age and sex
NAFLD nonalcoholic fatty liver disease, BMI body mass index, SBP systolic blood pressure, DBP diastolic blood pressure, ALT alanine aminotransferase, LDL low-density lipoprotein, HDL high-density lipoprotein, FPG fasting plasma glucose
* Data was unadjusted