Table 3.

Patient characteristics and other factors evaluated for their associations with serological outcomes after syphilis therapy

First Author	PatientAge	Patient Gender	Baseline nontrepo-nemal titers	Stage of syphilis infection	History of prior syphilis	Trepo-nemal IgM	Syphilis treatment regimen	HIV coinfection	CD4 cell count	HIV viral load	Antiretroviral therapy
Dionne-Odom		+	+	+				—
Fiumara			+
Ghanem (2007) [23]				—				+
Goemen								—
Knaute				+				—
Li			+	+		+
Long			+				—	—
Manavi	—		+		+	—		—
Reidner	—	—	+	+			—	—
Rolfs					—		—	+
Romanowski	—	—	+	+	+
Seña	+		+	+	—		—
Tittes	+	—	+	—			+	—
Tong	+	+	+	+
Ghanem (2008) [24]	+						—	H	+	—	+
Jinno	—		+	—	+		—	H	+	—	—
Malone								H	—
Tsai	+				—		—	H	—	—	—
Wu	—		—	+				H	—	—	—
Yang			+	+	—		+	H	—	—	—

H indicates that the study included HIV-infected participants only

+ indicates a significant association in multivariate analyses between the variable and serological outcomes after therapy

– indicates that a significant association was not identified between the variable and serological outcomes after therapy