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. 2015 Oct 29;14:171. doi: 10.1186/s12934-015-0362-x

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© Radoš et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — A summary of the stepwise systematic approach used to engineering C. glutamicum for the production of 2,3-BD. The values reflect the impact of the several steps on yield and productivity. Blue boxes refer to strain optimization steps, while the yellow box indicates the process optimization step. 2,3-BD 2,3-butanediol, Glc glucose