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. 2015 Sep;10(9):1483–1490. doi: 10.4103/1673-5374.165521

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Copyright: © Neural Regeneration Research

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bcl-2 and Caspase-3 mRNA expression in the injured regions of the SCI rats in each group.

(A) Compared with the SCI group, Caspase-3 gene expression was obviously lower, but bcl-2 gene expression was higher in the hEPO-NSCs group. (B) Significant differences in the relative optical density values (/GAPDH) for both the Caspase-3 and bcl-2 mRNA expression levels were detected between groups (P < 0.05; mean ± SD, n = 5, one-way analysis of variance and the least significant difference test). SCI: Spinal cord injury; hEPO: human erythropoietin; NSCs: neural stem cells; GAPDH: glyceraldehyde phosphate dehydrogenase.