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. 2015 Sep;10(9):1483–1490. doi: 10.4103/1673-5374.165521

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Copyright: © Neural Regeneration Research

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Pathological changes in the injured regions of the SCI rats from all groups.

Hematoxylin-eosin staining showed that a cavity formed in the spinal cord of the SCI group. The cavity was small in the NSCs group, but had nearly disappeared in the hEPO-NSCs group. The numbers of CM-Dil-positive cells and HRP-positive nerve fibers were larger in the hEPO-NSCs group than in the NSCs group, and smallest in the SCI group (P < 0.01; mean ± SD, n = 5, one-way analysis of variance and the least significant difference test). SCI: Spinal cord injury; NSCs: neural stem cells; hEPO: human erythropoietin; HRP: horseradish peroxidase.