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. 2015 Sep;10(9):1498–1506. doi: 10.4103/1673-5374.165523

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Copyright: © Neural Regeneration Research

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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BDNF and CNTF protein expression in the rat nerve tissue harvested from transplantation site (western blot assay).

1: CEANA group; 2: CEANA + BDNF/BMSCs group; 3: CEANA + CNTF/BMSCs group; 4: CEANA + BDNF + CNTF/BMSCs group; 5: CEANA/BMSCs group. Recombinant plasmids pIRES-BDNF and pIRES-BDNF-CNTF were normally expressed in the nerve allografts normally expressed in the nerve allografts in the CEANA + BDNF/BMSCs and CEANA + BDNF + CNTF/BMSCs groups. Recombinant plasmids pIRES-CNTF and pIRES-BDNF-CNTF were normally expressed in the nerve allografts in the CEANA + CNTF/BMSCs and CEANA + BDNF + CNTF/BMSCs groups. CEANA: Chemically extracted acellular nerve allografts; BDNF: brain-derived neurotrophic factor; CNTF: ciliary neurotrophic factor; BMSCs: bone marrow mesenchymal stem cells. GAPDH: Glyceraldehyde phosphate dehydrogenase.