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. Author manuscript; available in PMC: 2015 Oct 29.
Published in final edited form as: J Mol Biol. 2007 Mar 6;368(5):1321–1331. doi: 10.1016/j.jmb.2007.02.085

Figure 3.

Figure 3

Location of the RF61 epitopes on Fc recognized by RF61 Fab. The Cγ3 domains of each of the two heavy chains (colored light and dark-blue) are viewed (a) in the same orientation as in Figure 2 and (b) at 90° to view (a), along the 2-fold axis looking onto the C-terminal end of the Fc. The Cγ3 residues involved in the interactions with each of the two Fabs are shown in yellow and purple; view (b) shows that each epitope spans the two Cγ3 domains. Residue Arg355 in each heavy chain is indicated.