Table 2.
YF MAC-HD results of serum samples from confirmed flavivirus and Malaria infections.
| Sample | Confirmed Dx | Dx result* | YF MAC-HD P/N |
|---|---|---|---|
| 1 | DEN | 62.1 | 3.7 |
| 2 | DEN | 58.9 | 1.1 |
| 3 | DEN | 11.6 | 2.2 |
| **4 | DEN | 15.1 | 14.1 |
| 5 | DEN | 19.3 | 4.1 |
| 6 | DEN | 19.4 | 9 |
| 7 | DEN | 16.7 | 2.9 |
| 8 | DEN | 11.5 | 3.2 |
| 9 | WN | 9 | 5.7 |
| 10 | WN | 4.7 | 1 |
| 11 | WN | 6.4 | 0.9 |
| 12 | WN | 21.2 | 12.6 |
| 13 | WN | 22.4 | 0.5 |
| 14 | WN | 3 | 1 |
| 15 | WN | 7.4 | 0.9 |
| 16 | ZIKA | 12.1 | 0.7 |
| 17 | ZIKA | 11.1 | ***1.2 |
| 18 | ZIKA | 6.6 | 0.6 |
| 19 | ZIKA | 8.1 | 3.6 |
| 20 | ZIKA | 36.1 | 0.6 |
| 21 | ZIKA | 4.4 | 0.7 |
| 22 | ZIKA | 15.6 | 0.6 |
| 23 | ZIKA | 13.3 | 7.2 |
| 24 | Malaria | POS | 0.8 |
| 25 | Malaria | POS | ***bkgd |
| 26 | Malaria | POS | 1 |
| 27 | Malaria | POS | 0.6 |
| 28 | Malaria | POS | 0.6 |
| 29 | Malaria | POS | 0.8 |
| 30 | Malaria | POS | ***bkgd |
| 31 | Malaria | POS | ****4.2 |
Diagnostic results presented are IgM ELISA P/N for DEN, WN and ZIKA where P/N 2.0>=3.0 is equivocal and P/N>=3.0 is positive; CareStart rapid antigen test was used for malaria
Sample 4 is a secondary DEN infection as determined by PRNT where there is a <4-fold difference in titer between results for each of the 4 serotypes
Samples 17, 25 and 30 were confirmed as negative by YF MAC-ON
Sample 31 was negative by YF and DEN1/2 PRNT; positive by YF IgM IFA, positive YF MAC-ON, equivocal by YF CDC MAC-ELISA and negative by WN and DEN CDC MAC-ELISA