Table 3.
Univariate and multivariate analysis for radiographic predictors of Local Control (LC) for all patients
Univariate | Multivariate | ||
---|---|---|---|
Variable | P-value | HR (95 % CI) | P-value |
Total Dose (Gy) | 0.001* | 0.999 (0.998 to 1.001) | 0.209 |
Number of Fractions | 0.189 | 1.004 (0.849 to 1.185) | 0.966 |
Dose per Fractions (≥9 Gy) | 0.021 | 0.726 (0.469 to 1.124) | 0.153 |
BED (100 Gy) | 0.005* | 0.264 (0.022 to 3.119) | 0.293 |
Site (Thorax vs Other) | 0.185 | 1.941 (0.515 to 7.323) | 0.329 |
Time from Primary Diagnosis | 0.318 | 0.996 (0.980 to 1.012) | 0.663 |
Male Gender | 0.048 | 0.481 (0.120 to 1.915) | 0.301 |
Age | 0.610 | 0.990 (0.916 to 1.071) | 0.816 |
Smoker | 0.123 | 0.276 (0.058 to 1.311) | 0.107 |
Greater than 5 Metastatic Lesions | 0.808 | 0.674 (0.170 to 2.673) | 0.577 |
Pre-Radiation Systemic Therapy | 0.517 | 2.299 (0.605 to 8.724) | 0.223 |
Post-Radiation Systemic Therapy | 0.332 | 0.201 (0.038 to 1.037) | 0.056 |
BED biologic effective dose, HR hazard ratio, CI confidence interval
*-Statistically significant values