Table 5.
Univariate and multivariate analysis for radiographic predictors of Local Control (LC) for CF-EBRT patients
| Univariate | Multivariate | ||
|---|---|---|---|
| Variable | P-value | HR (95 % CI) | P-value |
| Total Dose (Gy) | 0.025* | 0.994 (0.986 to 1.003) | 0.216 |
| Number of Fractions | 0.114 | 0.872 (0.698 to 1.090) | 0.232 |
| Dose per Fractions (≥9 Gy) | 0.950 | 0.729 (0.195 to 2.725) | 0.640 |
| BED (100 Gy) | 0.017* | 3.94 (0.028 to 2.345) | 0.325 |
| Site (Thorax vs Other) | 0.867 | 1.579 (0.404 to 6.173) | 0.513 |
| Time from Primary Diagnosis | 0.714 | 0.987 (0.961 to 1.015) | 0.386 |
| Male Gender | 0.653 | 1.003 (0.244 to 4.128) | 0.995 |
| Age | 0.560 | 0.953 (0.860 to 1.056) | 0.366 |
| Smoker | 0.172 | - | - |
| Greater than 5 Metastatic Lesions | 0.933 | 0.886 (0.216 to 3.623) | 0.867 |
| Pre-Radiation Systemic Therapy | 0.536 | 2.340 (0.586 to 9.345) | 0.231 |
| Post-Radiation Systemic Therapy | 0.417 | 0.206 (0.035 to 1.242) | 0.086 |
BED biologic effective dose, HR hazard ration, CI confidence interval
*-Statistically significant values