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. 2015 Oct 29;34:133. doi: 10.1186/s13046-015-0245-3

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© Lv et al. 2015

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Silencing HOXD9 in liver cancer cells decrease the migration and invasion of liver cancer cells. a Western blot analysis of HOXD9 levels in the established cell lines. b qRT-PCR analysis of HOXD9 levels in the established cell lines. c Liver cancer cells with silent expression of HOXD9 exhibit less invasive abilities in Transwell and Matrigel assays. d Silencing HOXD9 significantly decreased the number of mice with distant metastasis. e and f Fewer metastatic foci in the liver were observed in each mouse injected with liver cancer cell silencing HOXD9. P < 0.01 is based on Student’s t- test. Error bars, SD