Table 2.
APOL1 genotype distribution among patients with HIVAN, HIV-positive patients with CKD, HIV-negative patients with CKD, and controls
| Genotype | HIV-Positive Patients and Controls | HIV-Negative Patients and Controls | |||
|---|---|---|---|---|---|
| HIVANa | CKDb | HIV-Positive Controls | CKDc | Population Controls | |
| 0 risk alleles | |||||
| G0/G0 | 2 (5.3) | 22 (56.4) | 34 (63.0) | 25 (64.1) | 36 (66.7) |
| 1 risk allele | 6 (15.8) | 11 (28.2) | 18 (33.3) | 13 (33.3) | 17 (31.5) |
| G0/G1 | 5 (13.2) | 4 (10.3) | 4 (7.4) | 6 (15.4) | 7 (13.0) |
| G0/G2 | 1 (2.6) | 7 (17.9) | 14 (25.9) | 7 (17.9) | 10 (18.5) |
| 2 risk alleles | 30 (78.9) | 6 (15.4) | 2 (3.7) | 1 (2.6) | 1 (1.9) |
| G1/G1 | 8 (21.0) | 2 (5.1) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
| G1/G2 | 19 (50.0) | 2 (5.1) | 0 (0.0) | 1 (2.6) | 0 (0.0) |
| G2/G2 | 3 (7.9) | 2 (5.1) | 2 (3.7) | 0 (0.0) | 1 (1.9) |
| Total | 38 | 39 | 54 | 39 | 54 |
Data are given as n (%). The distribution of APOL1 genotypes and fractions with one or two risk alleles for the study groups is shown.
a
One patient did not pass genotyping.
b
The single HIV-positive patient with CKD carrying the G1+M (A-G-I) haplotype is excluded from this table and one patient did not pass genotyping.
c
Two patients did not pass genotyping.