Table 1.
Patient Characteristics according to the Number of High-Risk Findings at Baseline
| Characteristic | Total (n=862) | No. of high-risk findings* | p-value | |||
|---|---|---|---|---|---|---|
|
| ||||||
| 0 (n=429) | 1 (n=241) | 2 (n=118) | 3–4 (n=74) | |||
| Age, yr | 61.5±10.4 | 59.9±10.2 | 61.5±11.0 | 61.7±10.3 | 65.5±8.6 | <0.001 |
| <50 | 118 (13.7) | 64 (14.9) | 38 (15.8) | 13 (11.0) | 3 (4.1) | 0.01 |
| 50–59 | 250 (29.0) | 139 (32.4) | 56 (23.2) | 38 (32.2) | 17 (23.0) | |
| 60–69 | 291 (33.8) | 142 (33.1) | 83 (34.4) | 39 (33.1) | 27 (36.5) | |
| ≥70 | 203 (23.5) | 84 (19.6) | 64 (26.6) | 28 (23.7) | 27 (36.5) | |
| Sex | ||||||
| Male | 632 (73.3) | 298 (69.5) | 186 (77.2) | 89 (75.4) | 59 (79.7) | 0.08 |
| Female | 230 (26.7) | 131 (30.5) | 55 (22.8) | 29 (24.6) | 15 (20.3) | |
| No. of adenomas | 2.6±2.3 | 1.3±0.5 | 3.5±2.2 | 3.9±3.1 | 4.7±3.7 | <0.001 |
| 1 or 2 | 567 (65.8) | 429 (100) | 77 (32.0) | 41 (34.7) | 20 (27.0) | <0.001 |
| ≥3 | 295 (34.2) | 0 | 164 (68.0) | 77 (65.3) | 54 (73.0) | |
| Size of the largest adenoma, mm | 9.0±6.6 | 5.7±2.4 | 8.6±5.0 | 14.8±7.4 | 19.9±9.0 | <0.001 |
| ≤10 | 668 (77.5) | 429 (100) | 199 (82.6) | 34 (28.8) | 6 (8.1) | <0.001 |
| >10 | 194 (22.5) | 0 | 42 (17.4) | 84 (71.2) | 68 (91.9) | |
| Histology of adenoma | ||||||
| Tubular adenoma | 772 (89.6) | 429 (100) | 235 (97.5) | 87 (73.7) | 21 (28.4) | <0.001 |
| Tubulovillous or villous adenoma | 90 (10.4) | 0 | 6 (2.5) | 31 (26.3) | 53 (71.6) | |
| Dysplasia grade | ||||||
| Low-grade | 729 (84.6) | 429 (100) | 212 (88.0) | 67 (56.8) | 14 (18.9) | <0.001 |
| High-grade | 133 (15.4) | 0 | 29 (12.0) | 44 (37.3) | 60 (81.1) | |
| Nonadvanced adenoma | 593 (68.8) | 429 (100) | 164 (68.0) | 0 | 0 | <0.001 |
| Advanced adenoma† | 269 (31.2) | 0 | 77 (32.0) | 118 (98.3) | 74 (100) | |
Data are presented as mean±SD or number (%).
*
High-risk findings of baseline colonoscopy were defined as follows: adenoma with villous histology, high-grade dysplasia, size >10 mm, or 3 or more adenomas;
†
Advanced adenoma was defined as adenoma with villous histology, high-grade dysplasia, or size >10 mm.