Table 4.

Risk of Metachronous Advanced Neoplasia according to the Number of High-Risk Findings at Baseline

	Univariate analysis			Multivariate analysis*
	HR	95% CI	p-value	HR	95% CI	p-value
Age, yr	1.01	0.98–1.03	0.52	0.99	0.97–1.02	0.88
Male sex	1.19	0.69–2.06	0.54	1.06	0.61–1.86	0.84
No. of follow-up colonoscopies during study period	0.95	0.69–1.32	0.78	0.82	0.59–1.15	0.26
No. of high-risk findings detected on baseline colonoscopy†	1.67	1.38–2.03	<0.001	1.72	1.40–2.11	<0.001

HR, hazard ratio; CI, confidence interval.

^*Adjustment for age, gender, number of follow-up colonoscopies during the study period, and number of high-risk baseline findings;

^†High-risk baseline findings were defined as follows: adenoma with villous histology, high-grade dysplasia, size >10 mm, or 3 or more adenomas.