. 2015 Oct 29;15:480. doi: 10.1186/s12879-015-1223-2

Table 6.

Susceptibility of E. coli and P. aeruginosa isolates to commonly used antibiotics.

Unit	Organism and antibiotic	Pre-intervention	Post-intervention	p-value
TNICU
	E. coli
	ampicillin	42/83 (51)	40/76 (53)	0.80
	cefazolin	70/83 (84)	61/76 (80)	0.50
	cefotaxime	72/83 (87)	64/76 (84)	0.65
	ciprofloxacin	68/83 (82)	60/76 (79)	0.64
	TMP-SMX	66/83 (80)	61/76 (80)	0.91
	piperacillin-tazobactam	70/83 (84)	63/76 (83)	0.81
	imipenem	85/85 (100)	76/77 (99)	0.48^a
	gentamicin	77/83 (93)	70/76 (92)	0.87
	tobramycin	76/83 (92)	70/76 (92)	0.90
	P. aeruginosa
	ceftazidime	27/30 (90)	22/23 (96)	0.62^a
	ciprofloxacin	27/30 (90)	18/23 (78)	0.27^a
	piperacillin-tazobactam	27/30 (90)	22/23 (96)	0.62^a
	imipenem	30/30 (100)	20/23 (87)	0.076^a
	gentamicin	28/30 (93)	23/23 (100)	0.50^a
	tobramycin	30/30 (100)	23/23 (100)	-
MSICU
	E. coli
	ampicillin	37/95 (39)	30/81 (37)	0.79
	cefazolin	65/95 (68)	59/81 (73)	0.52
	cefotaxime	73/95 (77)	64/81 (79)	0.73
	ciprofloxacin	46/95 (48)	49/81 (60)	0.11
	TMP-SMX	58/95 (61)	43/81 (53)	0.29
	piperacillin-tazobactam	64/95 (67)	59/80 (74)	0.36
	imipenem	93/95 (98)	81/82 (99)	1.00^a
	gentamicin	76/95 (80)	73/81 (90)	0.063
	tobramycin	72/95 (76)	72/81 (89)	0.025
	P. aeruginosa
	ceftazidime	50/64 (78)	42/58 (72)	0.46
	ciprofloxacin	58/64 (91)	41/58 (71)	0.0049
	piperacillin-tazobactam	50/64 (78)	40/58 (69)	0.25
	imipenem	51/64 (80)	41/58 (71)	0.25
	gentamicin	58/64 (91)	48/58 (83)	0.20
	tobramycin	62/64 (97)	56/58 (97)	1.00^a

Data are number of isolates susceptible/total number of isolates tested (%). All p-values calculated using Chi-square unless otherwise noted. A Bonferroni corrected significance threshold of 0.0033 was used. TMP-SMX, trimethoprim-sulfamethoxazole.

^aFisher’s Exact test