Table 1.
Polycystic ovary syndrome related signs, symptoms, comorbidities, medication, laboratory results, ultrasound findings and other phenotypes abstracted from the medical record to inform feature selection and model training for natural language processing (NLP) analysis
| Feature | Parameter | Source |
|---|---|---|
| PCO morphology | Ovarian volume >10 | Pelvic ultrasound |
| PCO morphology | ≥12 follicles or PCO morphology in text | Pelvic ultrasound |
| Hyperandrogenism | Elevated testosterone, DHEAS or androstenedione | Laboratory data |
| Hyperandrogenism | Hirsutism | Note |
| Hyperandrogenism | Ferriman Gallwey Score | Physical exam |
| Hyperandrogenism | Acne | Physical exam or note |
| Hyperandrogenism | Alopecia, Hair loss, balding | Physical exam or note |
| Irregular menses | Cycle length | Note |
| Irregular menses | Irregular menses, oligomenorrhea, amenorrhea, etc. | Note |
| Hyperandrogenism | Clitoromegaly | Physical exam |
| Associated Features | ||
| Acanthosis Nigricans | Acanthosis | Physical exam |
| Gestational Diabetes | Gestational diabetes | Note |
| Infertility | Anovulatory infertility | Note |
| Obesity | Obesity | Physical exam or note |
| Type 2 diabetes | Type 2 diabetes | Laboratory data or note |
| Pertinent Negatives | ||
| Excessive exercise | Exercise history | Note |
| Chronic opioid or drug use | Substance history | Note |
| Hypothalamic amenorrhea | BMI or Hypothalamic amenorrhea history | Physical exam or note |