. 2012 Jun 5;53(7):3331–3339. doi: 10.1167/iovs.11-9027

Table 4.

Predictors of Chromosome 3 Status

Variable	Levels	SNP Disomy 3	SNP Monosomy 3	Sensitivity	Specificity	PPV	NPV
FISH- CEP3	Disomy 3	15	7	0.78 (0.61, 0.89)	1.00 (0.80, 1.00)	1.00 (0.87, 1.00)	0.68 (0.47, 0.84)
FISH- CEP3	Monosomy 3	0	25	0.78 (0.61, 0.89)	1.00 (0.80, 1.00)	1.00 (0.87, 1.00)	0.68 (0.47, 0.84)
FISH- 3p26	Normal	15	2	0.94 (0.80, 0.98)	1.00 (0.80, 1.00)	1.00 (0.89, 1.00)	0.88 (0.66, 0.97)
FISH- 3p26	Deleted	0	30	0.94 (0.80, 0.98)	1.00 (0.80, 1.00)	1.00 (0.89, 1.00)	0.88 (0.66, 0.97)

For both FISH CEP3 and FISH 3p26, the sensitivity, specificity, positive predictive value, and negative predictive value were calculated using SNP-A as the gold standard. PPV, positive predictive value; NNP, negative predictive value. Values within parentheses indicate 95% confidence limits.