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. 2015 Sep 22;4(10):565–575. doi: 10.1002/psp4.12015

Figure 2.

Figure 2

Plot to visualize a prespecified analysis for establishing supportive evidence of effectiveness. Data points are mean and 95% CI of effects for quantiles of AUC values. The horizontal lines with diamonds along the abscissa represent medians and 90% exposure ranges at each dose level. Data was simulated with 8 active + 4 placebo subjects at the two lower dose levels, and 16 active + 8 placebo subjects at the highest dose level.