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. 2015 Oct 8;4(10):595–604. doi: 10.1002/psp4.12031

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© 2015 The Authors. CPT: Pharmacometrics & Systems Pharmacology published by Wiley Periodicals, Inc. on behalf of American Society for Clinical Pharmacology and Therapeutics

This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Population prediction of vitreous humor (a) and serum (b) concentration-time profiles with q4wk, q6wk, and q8wk of lampalizumab at dose level of 10 mg per eye. Black solid lines represent 50^th percentile of the population, and shaded regions represent 5^th−95^th prediction intervals.