Table 3.
Baseline differences in fatty acid profile and estimated desaturase activities in overweight and obese subjects
| Variable | BMI < 30 | BMI >30 | Δ (95 %) | P value |
|---|---|---|---|---|
| C16:0 | 26.7 ± 2.3 | 27.6 ± 2.8 | 0.84 (−1.84, 0.16) | 0.10 |
| C16:1 | 2.6 ± 0.9 | 2.9 ± 0.9 | −0.26 (−0.61, 0.08) | 0.14 |
| C18:0 | 6.0 ± 0.8 | 5.9 ± 0.7 | 0.16 (−0.15, 0.46) | 0.31 |
| C18:1 | 21.6 ± 3.3 | 22.9 ± 3.5 | −1.36 (−2.72, 0.0018) | 0.05 |
| C18:2 n-6 | 29.7 ± 4.0 | 27.7 ± 4.5 | 2.06 (0.39, 3.73) | 0.02 |
| C18:3 n-3 | 0.5 ± 0.2 | 0.5 ± 2 | 0.03 (−0.04, 0.10) | 0.42 |
| C18:3 n-6 | 0.3 ± 0.2 | 0.3 ± 0.2 | −0.0036 (−0.06, 0.06) | 0.91 |
| C20:3 n-6 | 1.4 ± 0.3 | 1.3 ± 0.3 | 0.04 (−0.07, 0.15) | 0.43 |
| C20:4 n-6 | 8.9 ± 1.5 | 8.5 ± 1.9 | 0.32 (−0.35, 1.00) | 0.35 |
| C20:5 n-3 | 0.5 ± 0.3 | 0.6 ± 0.3 | −0.02 (−0.14, 0.1) | 0.73 |
| C22:5 n-3 | 0.3 ± 0.2 | 0.3 ± 0.1 | 0.03 (−0.03, 0.09) | 0.27 |
| C22:6 n-3 | 1.5 ± 0.4 | 1.7 ± 0.6 | −0.16 (−0.36, 0.04) | 0.12 |
| AA/EPA | 20.2 ± 9.5 | 20.3 ± 11.0 | −0.09 (−4.08, 3.91) | 0.97 |
| Saturated fatty acids | 32.7 ± 2.4 | 33.4 ± 0.8 | −0.68 (−1.69, 0.33) | 0.18 |
| Monounsaturated fatty acids | 24.2 ± 3.4 | 25.8 ± 4.0 | −1.62 (−3.06, −0.19) | 0.03 |
| Polyunsaturated fatty acids (PUFA) | 43.1 ± 4.5 | 40.8 ± 5.3 | 2.31 (0.38, 4.23) | 0.02 |
| Total omega-6 PUFA | 40.2 ± 4.5 | 37.8 ± 5.3 | 2.42 (0.51, 4.34) | 0.01 |
| Total omega-3 PUFA | 2.9 ± 0.7 | 3.0 ± 0.9 | −0.12 (−0.44, 0.20) | 0.47 |
| omega-6/omega-3 | 14.8 ± 3.7 | 13.7 ± 4.0 | 1.06 (−0.46, 2.58) | 0.17 |
| Δ9C16:0 Desaturase | 0.1 ± 0.03 | 0.1 ± 0.03 | −0.01 (−0.02, 0.004) | 0.21 |
| Δ9C18:0 Desaturase | 3.7 ± 0.8 | 4.0 ± 0.9 | −0.34 (−0.68, −0.002) | 0.04 |
| Δ5 Desaturase | 6.8 ± 1.9 | 6.8 ± 2.0 | 0.05 (−0.69, 0.80) | 0.88 |
| Δ6 Desaturase | 0.01 ± 0.01 | 0.01 ± 0.01 | −0.0007 (−0.002, 0.001) | 0.47 |
Values in bold, p <0.05