Table 2.
Clinical and molecular characteristics of patients without mutations
| Patients without APC and MUTYH mutations | ||||
|---|---|---|---|---|
| Casea | Age at diagnosis | Phenotype | Family History (transmission) | Additional informations |
| GD70 | 43 | AFAP | yes (vertical) | |
| GD78 | 35 | Multiple polyposis | yes (vertical) | >10 polyps |
| GD80 | 45 | Multiple polyposis | yes (horizontal) | |
| GD81 | 36 | AFAP | yes (vertical) | |
| GD83 | 36 | FAP | yes (horizontal) | |
| GD84 | 32 | FAP | no | desmoids |
| GD86 | 17 | FAP | yes (vertical) | 143 microadenomas and 2 polyps |
| GD87 | 22 | FAP | no | rectal polyps, desmoids |
| GD92 | 58 | AFAP | n.a. | |
| GD94 | 65 | AFAP | yes (vertical) | 5 polyps, colon cancer |
| GD102 | n.a. | Multiple polyposis | n.a. | cystadenocarcinoma (unknown site) |
| GD106 | 50 | Multiple polyposis | n.a. | |
| GD107 | 42 | Multiple polyposis | yes (horizontal) | |
| GD109 | 52 | Multiple polyposis | no | 36 polyps, colon cancer |
| GD112#1 | 37 | FAP | yes (vertical) | colon, gastric, duodenal and rectal polyps |
| GD112#2 | 14 | FAP | yes (vertical) | colon and gastric polyps |
| GD117 | 63 | Multiple polyposis | yes (horizontal) | 10 polyps, gastric cancer |
| GD118 | 71 | AFAP | yes (vertical) | 10 polyps, colon cancer |
| GD121 | 41 | AFAP | n.a. | |
| GD122 | 59 | Colon cancer | yes (vertical) | |
| GD123 | 60 | AFAP | no | colon cancer |
| GD140 | 37 | AFAP | no | gastric polyps |
| GD146 | 44 | AFAP | no | colon and breast cancer |
| GD153 | 47 | AFAP | yes (horizontal) | hyperplastic polyps, colon cancer |
| GD154 | 44 | FAP | no | 836 polyps |
| GD157 | 53 | FAP | no | colon cancer |
| GD158 | 52 | FAP | yes (vertical) | |
| GD159 | 26 | FAP | yes (vertical) | rectal cancer |
| GD160 | 52 | AFAP | no | 10 polyps |