Table 1.
Sample characteristics of participants in Genetic Disease Screening Program of the California Department of Public Health
| First trimester | Second trimester | |
|---|---|---|
| n | 429,087 | 659,581 |
| Year [n (%)] | ||
| 2009 | 3,040 (0.7) | 80,360 (12) |
| 2010 | 147,522 (34) | 211,803 (32) |
| 2011 | 171,606 (40) | 228,423 (35) |
| 2012 | 106,895 (25) | 138,968 (21) |
| Fetal sex [n (%)] | ||
| Female | 209,520 (49) | 321,744 (49) |
| Male | 217,778 (51) | 334,907 (51) |
| Race/ethnicity [n (%)] | ||
| Asian | 56,632 (13) | 77,794 (12) |
| Black | 18,889 (4.4) | 32,315 (4.9) |
| Hispanic | 195,274 (46) | 322,041 (49) |
| White | 139,176 (32) | 198,836 (30) |
| Other | 19,114 (4.5) | 28,595 (4.3) |
| Diabetic [n (%)] | 4,554 (1.1) | 5,969 (0.9) |
| Current smoker [n (%)] | 3,462 (0.8) | 7,702 (1.2) |
| Ovum donor [n (%)] | 1,493 (0.4) | 1,794 (0.3) |
| Maternal age (years) [n (%)] | ||
| <20 | 18,716 (4.4) | 38,056 (6) |
| 20–34 | 310,576 (72.4) | 484,248 (73) |
| >34 | 99,763 (23.3) | 137,242 (21) |
| Maternal weight (kg) [n (%)] | ||
| ≤59 | 110,808 (26) | 166,857 (25) |
| 59–79 | 213,929 (50) | 326,001 (50) |
| 79< | 104,342 (24) | 166,715 (25) |
| Dating method [n (%)] | ||
| Last menstrual period | 12,264 (3) | 39,627 (6) |
| Nuchal translucency | 282,062 (66) | 299,373 (45) |
| Ultrasound | 134,761 (31) | 317,187 (48) |
| Physical exam | 3,394 (1) | |