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. 2015 Oct 29;14:423. doi: 10.1186/s12936-015-0918-6

Table 3.

Efficacy of ASAQ and AL as first-line and second-line treatments

First treated malaria episode ≥Second treated malaria episode
ASAQ
 ACPR, N (%) 59 (98.3) 37 (94.9) RR = 1.04 (0.96–1.12)
 Recrudescence, N (%) 1 (1.7) 2 (5.1) P = 0.3
 New infection 3 5
 Lost-to-follow-up 15 7
AL
 ACPR, N (%) 69 (94.5) 37 (100.0) RR = 0.95 (0.89–1.00)
 Recrudescence, N (%) 4 (5.5) 0 P = 0.19
 New infection 4 4
 Lost-to-follow-up 10 5
RR = 1.04 (0.98–1.11), P = 0.2 RR = 0.95 (0.88–1.02), P = 0.26

ASAQ artesunate-amodiaquine, AL artemether-lumefantrine, ACPR adequate clinical and parasitological response