Table 2.
Pretreatment | Treatment (p.o.) | Dose (mg/kg) | UI (mm) | Increase Lesion (%) |
---|---|---|---|---|
Saline | Saline | 10 | 27 ± 8 | - |
NEM (10 mg/Kg) | Saline | 10 | 76 ± 21** | 181 |
NEM (10 mg/Kg) | Sa-FRF | 100 | 53 ± 11** | 96 |
NEM (10 mg/Kg) | Sa-FDF | 100 | 56 ± 13** | 107 |
Saline | Saline | 10 | 27 ± 8 | - |
NEM (10 mg/Kg) | Saline | 10 | 83 ± 14* | 207 |
NEM (10 mg/Kg) | Sb-FRF | 100 | 56 ± 11* | 107 |
NEM (10 mg/Kg) | Sb-FDF | 100 | 69 ± 17* | 155 |
ANOVA followed by Dunnett’s test.* p < 0.05, ** p < 0.01. Data are presented as mean ± S.D (n = 5-7)