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. Author manuscript; available in PMC: 2015 Oct 29.
Published in final edited form as: J Biomed Mater Res B Appl Biomater. 2012 Jan 25;100(3):850–861. doi: 10.1002/jbm.b.32649

FIGURE 5.

FIGURE 5

Effects of silorane on collagen matrix formation and alkaline phosphatase. Immunohistochemical staining of collagen type 1 fibers in the control (left) and SilMix (right) revealed an intact collagen network that appeared thicker in the SilMix resin drop cultures (A). (×10 magnification). No negative effects were observed on collagen matrix formation at 6 days of culture. At 6 days, significantly elevated alkaline phospha tase was observed in the SilMix containing cultures compared to the control. No alkaline phosphatase was detected in the BT cultures at 6 days (B). *Significantly different from cells alone (p < 0.05) and from BT (p < 0.001) using one way ANOVA and Tukey post test. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]