Table 2. Gene expression at different time points (2, 4, 8, 12 and 24 hours) following p37 (5 μg ml-1) addition to NIH3T3 fibroblasts.
| 5 μg ml-1 p37 | 25 μg ml-1 p37 | |||||
|---|---|---|---|---|---|---|
| 2 hours | 4 hours | 8 hours | 12 hours | 24 hours | 24 hours | |
| Angptl4 | 108 | 202 | 68 | 35 | 3 | 20 |
| Saa3 | 46 | 80 | 66 | 15 | 7 | 197 |
| IL6 | 42 | 98 | 7 | 4 | 1 | 3 |
| Vcam1 | 17 | 21 | 3 | 1 | 1 | 2 |
| Dcn | 8 | 5 | 1 | 1 | 2 | 11 |
| LIF | 3 | 5 | 1 | 1 | 5 | 5 |
| Tm4sf1 | 3 | 3 | 4 | 2 | 1 | 3 |
| Hp | 2 | 2 | 5 | 7 | 7 | 8 |
| Lcn2 | 2 | 2 | 3 | 4 | 23 | 96 |
| Mmp9 | 2 | 2 | 2 | 2 | 4 | 5 |
| Cp | 2 | 2 | 2 | 2 | 2 | 2 |
| Thbp1 | 2 | 2 | 1 | 2 | 1 | 1 |
| C3 | 2 | 1 | 1 | 1 | 13 | 54 |
| Has2 | 2 | 1 | 1 | 1 | 2 | 5 |
| TNFαip6 | 1 | 1 | 1 | 2 | 2 | 2 |
| Lum | 1 | 1 | 1 | 1 | 1 | 3 |
| Cast | 1 | 1 | 1 | 1 | 1 | 2 |
| Fkbp5 | 1 | 1 | 1 | 1 | 1 | 1 |
Fold change (E-ΔΔCt) of mRNA expression levels of NIH3T3 fibroblasts treated with 5 μg ml-1 p37 at 2, 4, 8, 12 or 24 hours. The 25 μg ml-1 p37 for 24 hours results are presented for comparison. Significant differences between treated and untreated cells were calculated by ANOVA analysis (p-values ≤0.05 are shown in bold).