Table 1. Biacore assay results of binding affinity between recombinant human proteasome β1 subunit and fangchinoline or tetrandrine.
Compound | Association (k a) (M-1S-1) | Dissociation (k d) (S-1) | Equilibrium dissociation (K D) (μM) |
---|---|---|---|
fangchinoline | 7.55×103 | 0.0353 | 4.68 |
tetrandrine | 2.89×103 | 0.0162 | 5.61 |