Figure 1.

Protein expression levels of P-gp with or without arsenic trioxide treatment for 48 h, determined using western blotting. 1, protein expression of P-gp in SGC7901/ADM cells treated with 0.1 µM As₂O₃ for 48 h; 2, protein expression of P-gp in SGC7901/ADM cells treated with 0.5 µM As₂O₃ for 48 h; 3, protein expression of P-gp in SGC7901/ADM cells treated with 4 g/ml CsA for 48 h; 4, protein expression of P-gp in SGC7901/ADM cells without As₂O₃; 5, protein expression of P-gp in SGC7901/S without As₂O₃. P-gp, p-glycoprotein; CsA, cyclosporin A; As₂O₃, arsenic trioxide.