Figure 5.

Immunohistochemistry of (A) p-ERK1/2 protein in the SGC7901/ADM cells following treatment with As₂O₃ (0.1 µM) and rhG-CSF for 48 h; (B) p-ERK1/2 protein in the SGC7901/ADM cells following treatment with 0.5 µM As₂O₃ and rhG-CSF for 48 h (magnification, ×400). Treatment with 0.10 and 0.50 µM As₂O₃ reduced the levels of p-ERK1/2, compared with the negative control group. p-ERK, phosphorylated extracellular signal-regulated kinase; rhG-CSF, recombinant human granulocyte colony stimulating factor; As₂O₃, arsenic trioxide.