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Effect of IMD on the expression of M-CSF. The mRNA and protein expression levels of M-CSF in the MC3T3-E1 cells were measured following treatment with (1–100 nM) IMD for 48 h. Treatment with 100 nM IMD significantly decreased the mRNA and protein expression levels of M-CSF. #P<0.01. Data are presented as the mean ± standard deviation. IMD, inter-medin; M-CSF, macrophage colony-stimulating factor.
