Table 1. Amino acid sequence and physicochemical properties of esculentin-2CHa and its substituted analogues.
| Peptide | Sequence | Net charge at pH 7 | Isoelectric point |
|---|---|---|---|
| Esculentin-2CHa | GFSSIFRGVAKFASKGLGKDLAKLGVDLVACKISKQC | 5 | 10.82 |
| [L21K]Esculentin-2CHa | GFSSIFRGVAKFASKGLGKDKAKLGVDLVACKISKQC | 6 | 10.91 |
| [L24K]Esculentin-2CHa | GFSSIFRGVAKFASKGLGKDLAKKGVDLVACKISKQC | 6 | 10.91 |
| [L28K]Esculentin-2CHa | GFSSIFRGVAKFASKGLGKDLAKLGVDKVACKISKQC | 6 | 10.91 |
| [C31K]Esculentin-2CHa | GFSSIFRGVAKFASKGLGKDLAKLGVDLVAKKISKQC | 6 | 10.65 |
| [C31S,C37S]Esculentin-2CHa | GFSSIFRGVAKFASKGLGKDLAKLGVDLVASKISKQS | 5 | 10.82 |
| [D20K, Lys27]Esculentin-2CHa | GFSSIFRGVAKFASKGLGKKLAKLGVKLVACKISKQC | 9 | 11.97 |