. Author manuscript; available in PMC: 2016 Nov 1.

Published in final edited form as: Arthritis Rheumatol. 2015 Nov;67(11):2933–2943. doi: 10.1002/art.39291

Table 1.

Calcium imaging of DRG neurons

Type of Imaging	Protein tested	(# neuronal responses)/(total # capsaicin-sensitive neurons), (%)	(# neuronal responses)/(total # non-capsaicin-sensitive neurons), (%)	(# neuronal responses)/(total # neurons), (%)	p-value (capsaicin-sensitive vs non-capsaicin-sensitive)	number of independent experiments
Naïve in vitro	S100A8 (1 μg/mL)	10/127 (8%)	4/134 (3%)	14/261 (5%)	0.1011	3
DMM+8 in vitro	S100A8 (1 μg/mL)	18/82 (22%)	5/52 (10%)	23/134 (17%)	0.0984	3
Naïve in vitro	α₂-macroglobulin (100 μg/mL)	23/98 (23%)	10/120 (8%)	33/218 (15%)	0.0023	3
DMM+8 in vitro	α₂-macroglobulin (100 μg/mL)	15/76 (20%)	7/81 (9%)	22/157 (14%)	0.0646	3
Naïve in vitro	LPS (1 μg/mL)	5/52 (10%)	1/54 (2%)	6/106 (6%)	0.11	1
Naïve ex vivo	LPS (50 μg/mL)	30/104 (29%)	0/82 (0%)	30/186 (16%)	<0.0001	2