Table A1.
Comparison of empirical with model-based estimates of the correlation between repeat biomarker measurements as a function of the time between the repeats: protein density in men and women
| Empirical | Model-based | |||||
|---|---|---|---|---|---|---|
| Gender | Difference in Time Periods | Total no. individuals | Estimated correlation | 95% CI lower limit | 95% CI upper limit | Estimated Correlation |
| Men | 0 | 500 | 0.591 | 0.531 | 0.645 | 0.626 |
| 1 | 19 | 0.604 | 0.207 | 0.830 | 0.554 | |
| 2 | 16 | 0.706 | 0.323 | 0.890 | 0.554 | |
| 3 | 12 | 0.831 | 0.490 | 0.951 | 0.554 | |
| 4 | 9 | 0.880 | 0.521 | 0.975 | 0.554 | |
| 5 | 32 | 0530 | 0.222 | 0.741 | 0.554 | |
| 6 | 0 | - | - | - | 0.554 | |
| 7 | 8 | 0.480 | −0.339 | 0.885 | 0.554 | |
| Women | 0 | 550 | 0.604 | 0.548 | 0.654 | 0.602 |
| 1 | 109 | 0.367 | 0.192 | 0.519 | 0.477 | |
| 2 | 126 | 0.217 | 0.043 | 0.377 | 0.377 | |
| 3 | 20 | 0.120 | −0.341 | 0.534 | 0.299 | |
| 4 | 11 | 0.772 | 0.321 | 0.938 | 0.237 | |
| 5 | 20 | 0.483 | 0.051 | 0.762 | 0.188 | |
| 6 | 1 | - | - | - | 0.149 | |
| 7 | 12 | −0.259 | −0.725 | 0.370 | 0.118 | |