Table 3.

Proportion of children with apnea related outcomes in each group.

Outcome	Intention to treat - RA N=355	Intention to treat – GA N=356	As per protocol - RA N=286	RA to partial GA/sedation N=23	RA to full GA N=46
Any apnea (0–12hr)	10 (3%)	15 (4%)	6 (2%)	0	4 (9%)
Any early apnea (0–30min)	3 (1%)	12 (3%)	1 (<1%)	0	2 (4%)
Any late apnea (30min–12hr)	8 (2%)	7 (2%)	6 (2%)	0	2 (4%)
Any late apnea if discharged >=12hrs post-op	8 (3%)	6 (2%)	6(3%)	0	2 (5%)
Required significant intervention for apnea (0–5days)*	7 (2%)	18 (5%)	4 (1%)	0	3 (7%)
Required significant intervention for apnea (0–30min)*	1 (<1%)	12 (3%)	0	0	1 (2%)
Required significant intervention for apnea (30min–12hr)*	5 (1%)	5 (1%)	3 (1%)	0	2 (4%)
Required significant intervention for late apnea if discharged >=12hrs post-op	5 (2%)	5 (2%)	3(1%)	0	2 (5%)
Required significant intervention for apnea after 12 hrs (12hr–5days)*	2 (1%)	4 (1%)	2 (1%)	0	0
Any caffeine administered post-operatively (0–5days)	2 (1%)	4 (1%)	2 (1%)	0	0

GA= General Anesthesia; Hr = Hours; Min = Minutes; RA = Regional Anesthesia.

Data are presented as percentages of non-missing data. Partial GA/sedation is defined as receiving sevoflurane for only some of the surgery or receiving sedation. Full GA is defined as receiving sevoflurane from prior to knife to skin to the end of surgery.

^*Significant intervention for apnea is any intervention greater than simple tactile stimulation. GA as-per-protocol data are not presented as only 2 children in the GA arm had surgery cancelled so the data are very similar to the intention-to-treat data