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. Author manuscript; available in PMC: 2016 Nov 1.
Published in final edited form as: Arthritis Rheumatol. 2015 Nov;67(11):2990–3003. doi: 10.1002/art.39247

Figure 1. Cell-free DNA and NETs are increased in the circulation of patients with primary antiphospholipid syndrome (APS).

Figure 1

A, Cell-free DNA was measured in the plasma of APS patients (n=26) or healthy controls. B, Circulating NETs were measured in the same plasma by MPO-DNA ELISA. C, Cell-free DNA was measured in sera of APS patients (n=52) or healthy controls. D, Correlation between cell-free DNA and circulating NETs (MPO-DNA complexes) in APS sera. *p<0.05 and **p<0.01. In addition to the individual data points, mean and standard deviation are also presented in panels A–C.