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. 2015 Sep 30;17(3):166–172. doi: 10.7461/jcen.2015.17.3.166

Table 1. Clinical data and outcomes of the two groups.

AED group (n = 44) No AED group (n = 40) p value
Age (mean ± SD) 52.8 ± 12.7 52.4 ± 13.9 0.906
Gender 0.835
 Male 21 (47.7%) 20 (50.0%)
 Female 23 (52.3%) 20 (50.0%)
AED NA
 Levetiracetam Valproic acid NA
 Valproic acid 9 (20.5%) NA
Underlying disease 0.673
 HTN 9 (20.5%) 8 (20.0%)
 DM 3 (6.8%) 3 (7.5%)
 Dyslipidemia 6 (13.6%) 4 (10.0%)
 Smoking 8 (18.2%) 6 (15.0%)
Aneurysm location 0.104
 ICA 10 (22.7%) 11 (27.5%)
 ACA 15 (34.1%) 10 (25.0%)
 MCA 17 (38.6%) 9 (22.5%)
 Posterior circulation 2 (4.5%) 10 (25.0%)
Aneurysm shape 0.032
 Saccular 44 (100%) 36 (90.0%)
 Dissecting 0 (0%) 4 (10.0%)
Aneurysm size (mm, mean ± SD) 6.32 ± 2.94 7.65 ± 5.59 0.177
Initial HHG 0.990
 1 1 (2.3%) 0 (0.0%)
 2 29 (65.9%) 22 (55.0%)
 3 18 (40.9%) 14 (35.0%)
Fisher grade 0.980
 1 0 (0.0%) 0 (0.0%)
 2 7 (15.9%) 7 (17.5%)
 3 29 (65.9%) 26 (65.0%)
 4 8 (18.2%) 7 (17.5%)
EVD or Shunt 9 (20.5%) 5 (12.5%) 0.298
Hydrocephalus 10 (22.7%) 4 (10%) 0.254
Symptomatic vasospasm 7 (15.9%) 5 (12.5%) 0.772
Procedure related complication 3 (6.8%) 1 (2.5%) 0.621
Systemic complication 9 (20.5%) 2 (5.0%) 0.106
Treatment modality < 0.001
 Microsurgery 37 (84.1%) 7 (17.5%)
 Endovascular surgery 7 (15.9%) 33 (82.5%)
Clinical outcome at discharge 0.607
 Favorable (mRS 0~2) 38 (86.4%) 36 (90.0%)
 Poor (mRS 3~6) 6 (13.6%) 4 (10.0%)
Clinical outcome on 6-month 0.178
 Favorable (mRS 0~2) 38 (86.4%) 38 (95.0%)
 Poor (mRS 3~6) 6 (13.6%) 2 (5.0%)

ACA = anterior cerebral artery; AED = antiepileptic drug; DM = diabetes mellitus; EVD = external ventricular drainage; HTN = hypertension; ICA = internal carotid artery; MCA = middle cerebral artery; NA = not applicable; mRS = modified Rankin Scale; SD = standard deviation