Table 2.

Effect of EPL on anti-oxidant parameters of isoproterenol induced myocardial infarction in rats

Treatment groups	Catalase (U/mg protein)	SOD (U/mg protein)	GSH (µg/mg protein)
Normal	33.02±7.84	64.77±7.71	65.27±24.31
ISO	16.45±3.70###	23.11±8.92###	25.99±11.49###
EPL (50)	21.13±2.12	30.84±9.87	36.61±16.46*
EPL (100)	30.06±4.40**	73.08±12.83***	63.94±24.71***
EPL (150)	30.1±4.99*	60.35±8.022**	73.50±17.07***

Data was expressed as mean ± SEM;

^###p<0.001 as compared to normal;

^*p<0.05 as compared to ISO, Significance was determined by One-Way ANOVA followed by Dunnet Post-hoc test;

^**p<0.01 as compared to ISO, Significance was determined by One-Way ANOVA followed by Dunnet Post-hoc test;

^***p<0.001 as compared to ISO, Significance was determined by One-Way ANOVA followed by Dunnet Post-hoc test.

ISO: isoproterenol; EPL: eplerenone. The figure in the parenthesis indicates the dose in mg/kg.