Table 3.
Effect of eplerenone on histopathological changes in different experimental groups
| Treatment groups | Myonecrosis | Inflammatory cells | Edema |
|---|---|---|---|
| Normal | - | - | - |
| ISO | +++ | +++ | +++ |
| EPL (50) | ++ | + | ++ |
| EPL (100) | ++ | + | + |
| EPL (150) | + | - | + |
Severe (+++), moderate (++), mild (+) and nil (–).