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. Author manuscript; available in PMC: 2017 Jul 1.
Published in final edited form as: Addict Biol. 2015 Apr 29;21(4):802–810. doi: 10.1111/adb.12258

Figure 3. Cocaine-sired male offspring have increased hippocampal expression of CRFR2.

Figure 3

A) Cocaine-sired male (n=5 rats, 5 litters) offspring showed increased expression of Crhr2 transcript compared to saline-sired male offspring (n=4 animals, 4 litters). There was no effect of sire on Crf, Crhr1, Nr3c2, or Nr3c1 expression levels. B) Cocaine-sired male offspring (n=6, 5 litters) showed increased levels of CRFR2 protein compared to saline-sired male (n=4 rats, 4 litters). Western blots for CRFR2 and GAPDH are shown on the right. Data are shown as mean ± SEM, * p<0.05.