Table 1.
Virulence profiles of the 20 OII E. coli and 2 E. coli control strains studied.
| Site of | Phylogenetic | Virulence factorsb: | ||||
|---|---|---|---|---|---|---|
| Isolatea | infection | group | MLST | Serotype | fimH, papC, papGII, papGIII, sfa/foc, hra, tsh, iucC, hlyA, traT, sat, cnf1, usp, cdt, vat, ibeA, ompT, neuB, csgA and pgaA | Reference |
| Ec1 | Knee | B2 | ST95 | O2 | fimH, papC, papGII, iucC, traT, usp, vat, ompT, neuB, csgA and pgaA | This study |
| Ec2 | Knee | B2 | ST80 | O75 | fimH, sfa/foc, hra, hlyA, cnf1, usp, vat, ibeA, ompT, neuB, csgA and pgaA | This study |
| Ec3 | Hip | B2 | ST537 | O75 | fimH, papC, papGIII, sfa/foc, hra, hlyA, cnf1, usp, cdt, vat, ibeA, ompT, csgA and pgaA | This study |
| Ec4 | Knee | B2 | ST126 | - | fimH, papC, papGIII, sfa/foc, hra, hlyA, cnf1, usp, cdt, vat, ibeA, ompT, csgA and pgaA | This study |
| Ec5 | Hip | B2 | ST141 | O2 | fimH, papC, papGIII, sfa/foc, hra, hlyA, cnf1, usp, vat, ompT, neuB, csgA and pgaA | This study |
| Ec6 | Hip | B2 | ST404 | O75 | fimH, papGII, iucC, sat, usp, vat, ompT, csgA and pgaA | This study |
| Ec7 | Hip | B2 | ST73 | - | fimH, sfa/foc, hra, hlyA, cnf1, usp, vat, ompT, csgA and pgaA | This study |
| Ec8 | Hip | B2 | ST73 | O6 | fimH, papC, papGII, sfa/foc, iucC, hlyA, sat, usp, vat, ompT, csgA and pgaA | This study |
| Ec9 | Hip | B2 | ST550 | O75 | fimH, sfa/foc, iucC, sat, usp, vat, ompT, csgA and pgaA | This study |
| Ec10 | Hip | B2 | ST95 | O1 | fimH, papC, papGII, iucC, traT, usp, vat, ompT, neuB, csgA and pgaA | This study |
| Ec11 | Knee | B2 | ST141 | O2 | fimH, papC, papGIII, sfa/foc, hra, hlyA, cnf1, usp, vat, ompT, neuB, csgA and pgaA | This study |
| Ec12 | Hip | B2 | ST1618 | O4 | fimH, sfa/foc, usp, cdt, vat, ompT, csgA and pgaA | This study |
| Ec13 | Hip | B2 | ST95 | O1 | fimH, papC, papGII, iucC, traT, usp, vat, ompT, neuB, csgA and pgaA | This study |
| Ec14 | Hip | D | ST354 | O1 | fimH, iucC, traT, usp, ibeA and csgA | This study |
| Ec15 | Knee | D | ST405 | O2 | fimH, papC, hra, iucC, hlyA, traT, sat, ompT, csgA and pgaA | This study |
| Ec16 | Hip | D | ST420 | – | fimH, usp, vat, ibeA, ompT, neuB, csgA and pgaA | This study |
| Ec17 | Hip | A | ST361 | – | fimH, traT, csgA and pgaA | This study |
| Ec18 | Knee | A | ST88 | O8 | fimH, papC, hra, iucC, csgA and pgaA | This study |
| Ec19 | Hip | A | ST10 | – | fimH, papC, hra, iucC, traT, ompT, csgA and pgaA | This study |
| Ec20 | Hip | B1 | ST1167 | O21 | fimH, iucC, ompT, csgA and pgaA | This study |
| ZKLR± | – | B2 | – | O83 | fimH, papC, papGII, papGIII, sfa/foc, hra, tsh, hlyA, cnf1, usp, vat, ibeA, ompT, csgA and pgaA | (Sheshko et al. 2006) |
| Zhly_ | – | B2 | – | O83 | fimH, papC, papGII, papGIII, sfa/foc, hra, tsh, cnf1, usp, vat, ibeA, ompT, csgA and pgaA | (Sheshko et al. 2006) |
aE. coli strains that induced osteoblasts lysis in vitro are underlined.
bVirulence factors significantly associated with the osteoblasts lysis potential are shown in bold type.