Figure 6.

Comparison of known P5CR crystal structures. The presented enzymes originate from: MtP5CR/NADP⁺ complex (this work, light blue); HsP5CR/NAD⁺ (PDB ID: 2izz, orange); NmP5CR/NADP⁺ (2ag8, green); and SpP5CR/NADP⁺ (2ahr, purple). The protein molecules are shown as pipe-and-plank models, while the coenzymes are presented as ball-and-stick models. Secondary structure elements are denoted as: α, α-helices; η, 3₁₀ helices; β, β-strands.