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Pharmacokinetic parameters of fucoxanthin and fucoxanthinol in rats after i.g. (intragastric gavage) fucoxanthin administration at 65 mg/kg body wt.
| Parameters | Unit | Fucoxanthin | Fucoxanthinol | ||
|---|---|---|---|---|---|
| Mean | S.D. | Mean | S.D. | ||
| Cmax | μg/L | 29.1 | 4.4 | 263.3 | 93.9 |
| Tmax | h | 7.7 | 0.8 | 11 | 1.1 |
| AUC0–t | μg·h/L | 191.1 | 39.6 | 5017.6 | 1371.0 |
| AUC0–∞ | μg·h/L | 195.1 | 42.2 | 5304.2 | 1266.9 |
| t1/2 | h | 1.2 | 0.6 | 9.3 | 5.8 |
| CL | L/h/kg | 347.8 | 81.8 | 12.8 | 3.1 |
| Vd | L/kg | 550.2 | 226.1 | 181.5 | 142.4 |
