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. 2015 Oct 16;7(10):4175–4198. doi: 10.3390/toxins7104175

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© 2015 by the authors; licensee MDPI, Basel, Switzerland.

This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).

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Non-peptide mimetics of μ-conotoxin KIIIA by Baell and coworkers. The diketopiperazine carboxamide scaffold is highlighted in blue in 35 and 36. Activity is block of the Na_v1.7 channel (patch clamp assay) [72,73].