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Aged mice exhibit higher IL-6 and IL-1β plasma levels post-acute i.p. exposure to 1 mg/kg bw DON. (A) IL-6 plasma levels ng/mL and (B) IL-1β plasma levels pg/mL. Data are mean ± SEM (n = 4/replicates). Significant differences are indicated as follows: a = DON-dosed adults different from adult control; b = DON-dosed aged different from aged control; and c = DON-dosed aged different from DON-dosed adult (p < 0.05); d = vehicle control age groups different.
