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. 2015 Oct 26;21:1224–1234.

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Copyright © 2015 Molecular Vision.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited, used for non-commercial purposes, and is not altered or transformed.

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Scanning electron micrograph of lutein-loaded chitosan–dextran sulfate nanoparticles (LCDNs) obtained by formulation with PEG-400 and EDC (LCDN-PE). This was prepared by mixing chitosan (CS): dextran sulfate (DS) ratio of 1:1.67 (by weight), 0.001% w/v 1-ethyl-3-(3- dimethylaminopropyl)-carbodiimide hydrochloride (EDC), and 0.35% v/v polyethylene glycol-400 (PEG-400) with 0.005% v/v lutein aqueous solution. The particles show a spherical shape with uniform particle size distribution. Images for all other formulations showed similar morphology.