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. 2015 Oct 30;5:15674. doi: 10.1038/srep15674

Table 2. Summary of affected metabolic pathways in earthworm, Metaphire posthuma due to cypermethrin exposure.

Pathway Name Hits Metabolites Impact
Valine, leucine and isoleucine biosynthesis 4 Threonine, Leucine, Isoleucine, valine 0.625
Glycine, serine and threonine metabolism 3 Threonine, Serine, Glycine 0.42307
Ascorbate and aldarate metabolism 1 Myo-inositol 0.25
Galactose metabolism 3 Lactose, Glucose, Galactose 0.23077
Cyanoamino acid metabolism 3 Glycine, Serine, Alanine 0.2
Pantothenate and CoA biosynthesis 1 Valine 0.2
Aminoacyl-tRNA biosynthesis 7 Glycine, Serine, Vanine, Isoleucine, Leucine, Threonine, Proline 0.17776
Methane metabolism 2 Glycine, Serine 0.16667
Glyoxylate and dicarboxylate metabolism 1 Malic acid 0.14286
Inositol phosphate metabolism 1 Myo-inositol 0.11111
Pyruvate metabolism 1 Malic acid 0.09091
Arginine and proline metabolism 2 Proline, GABA 0.08333
Citrate cycle (TCA cycle) 1 Malic acid 0.06897
Glutathione metabolism 2 Pyroglutamic acid, Glycine 0.06896
Sphingolipid metabolism 1 Serine 0.06667
Butanoate metabolism 1 GABA 0.0625
Valine, leucine and isoleucine degradation 3 Valine, Leucine, Isoleucine 0.06249
Starch and sucrose metabolism 1 Glucose 0.05
Alanine, aspartate and glutamate metabolism 1 GABA 0.05
Cysteine and methionine metabolism 1 Serine 0.04348
Amino sugar and nucleotide sugar metabolism 1 Galactose 0.03571
Fatty acid metabolism 1 Hexadecanoic acid 0.02083
Nitrogen metabolism 1 Glycine 0.0
Fatty acid biosynthesis 2 Hexadecanoic acid, Tetradecanoic acid 0.0
Glycerophospholipid metabolism 1 Ethanol amine 0.0