Figure 6. Amiodarone induced autophagy via mTOR-independent signaling after PHx.

Wild-type mice were intraperitoneally injected with vehicle (Veh) or amiodarone (AD) at 0.5 h before PHx or the sham operation. Liver tissues were harvested at 0 h, 12 h, and 24 h after surgery and the total and phosphorylation status of mTOR, 4EBP1, and p70 S6K was assessed by Western blot analysis (A,B) (n = 6).