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. 2015 Oct 30;5:15807. doi: 10.1038/srep15807

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Copyright © 2015, Macmillan Publishers Limited

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Wild-type mice were intraperitoneally injected with vehicle (Veh), amiodarone (AD), or chloroquine (CQ) at 0.5 h before 90% PHx and then once per day until 168 h. (A) The survival rate was measured until 7 days after surgery (n = 12). (B) Serum ALT levels at 24 h after surgery (n = 6). (C) Liver tissues were harvested at 24 h after surgery and expression of PCNA protein was measured by Western blotting analysis. The values are shown as the mean ± SD in the bar graph and compared by Student’s t test. #P < 0.05 versus vehicle-treated PHx.